A Pancreas Transplant Alone (PTA) involves transplanting a pancreas from a cadaveric donor to a patient whose kidneys have not yet been affected by diabetes. It is performed on patients with Type I diabetes who are extremely brittle and/or challenged with significant and frequent hypoglycemia unawareness, or in cases where the risks of surgery and potential side effects of immunosuppression are better than the current state of health. To qualify for a pancreas alone transplant, candidates must be experiencing great difficulty in controlling glucose levels or experiencing other complications of diabetes. PTA's are the least common pancreas transplants.